GI Map Test UK : qPCR Stool Analysis for Gut Pathogens, Inflammation & Digestion
What is the GI-MAP Stool Test?
Are you struggling with digestive issues like bloating, diarrhoea, IBS symptoms, or recurrent infections? The GI-MAP test UK is one of the most advanced stool DNA tests available, helping uncover imbalances in your gut microbiome, infections, and markers of inflammation and digestion.
This page explains what the GI-MAP test measures, how it works, the benefits of choosing it in the UK, how much it costs, and what to expect from your results.
What Is the GI-MAP Test?
The Gastrointestinal Microbial Assay Plus (GI-MAP) is a stool test that uses qPCR (quantitative polymerase chain reaction) DNA technology. This method is more sensitive and accurate than traditional culture tests, detecting even small amounts of microbial DNA.
The test provides insight into:
Bacteria (beneficial, opportunistic, pathogenic)
Viruses
Fungi and yeast (including Candida species)
Parasites and worms
Inflammation and immune markers
Digestive function markers
Antibiotic resistance genes
- Zonulin – associated with “leaky gut”.
It is widely used in functional medicine and integrative health clinics across the UK, Europe, and the US.
Why Choose the GI-MAP Test? GI-MAP Test vs NHS Stool Test – What’s the Difference?
If you are experiencing persistent gut issues like IBS, inflammatory bowel disease (IBD), or digestive discomfort such as diarrhoea, constipation, or bloating, the GI-MAP test can offer clear insights. By detecting imbalances in the gut microbiome, this test can help address root causes of various conditions.
Most stool tests available through the NHS are designed to detect acute infections. If you have sudden diarrhoea or suspected food poisoning, the lab will usually check for a limited panel of common pathogens such as Salmonella, E. coli, Shigella or Campylobacter. These tests are very useful in emergencies but they do not provide detailed information about the balance of your gut microbiome, digestive enzyme output, or low-grade inflammation.
The GI-MAP test goes much further. It uses advanced DNA/qPCR technology to measure even very small amounts of microbes that are often missed in routine culture-based tests. It can detect:
The GI MAP test may help with the following conditions:
- IBS
- Skin conditions like acne and psoriasis
- Mood disorders such as depression and anxiety
- Autoimmune conditions
- Fatigue and brain fog
- Weight management challenges
- Diarrhea and digestive problems
- Foodborne illnesses
- Gastritis and viral gastroenteritis
- Gut dysbiosis (microbial imbalance)
- Inflammation and immune-related gut issues
- Detection of bacterial, parasitic, or viral infections (including antibiotic-resistant strains)
- Leaky gut
The test is carried out by Diagnostic Solutions.
How much does GI-MAP test cost UK?
Our GI Map test including Zonulin is £345 and is the most affordable on the market.
What does the GI-MAP test for?
Intestinal Permeability/ ‘leaky gut’
The test includes Zonulin- a marker for leaky gut and unlike other tests is included in the test fee.
Digestive Function
- Pancreatic Elastase 1-enzyme output, linked to digestion of fats/proteins
Elastase 1 is a digestive enzyme secreted exclusively by the pancreas, giving a direct indication of pancreatic function. - Occult Blood Fecal
Immunochemical Testing (FIT) - Steatocrit
Fecal fats are normally emulsified by bile salts and absorbed in the small intestines. High levels of fat in the stool may be an
indication of maldigestion, malabsorption. - Beta-Glucuronidase
High levels of fecal beta-glucuronidase can
indicate unfavorable metabolic changes in the colon.
Additional Gut Health Markers:
Inflammation and Immune markers
- Calprotectin: A gold-standard marker for inflammation, particularly useful in distinguishing Inflammatory bowel disease IBD from IBS.
Gut Bacteria
- Beneficial bacteria including Bacteroides fragilis, Bifidobacterium spp Lactobacillus spp. Akkermansia municiphila, Faecalibacterium prausnitzi and Enterococcus spp and Roseburia spp.
- Bad bacteria such as Klesbiella and Enterobacter Clocae, Streptococcus -sometimes linked to bloating, diarrhoea, IBS, or SIBO-like symptoms.
- Pathogenic bacteria: harmful species like Clostridium difficile, Salmonella, E. coli O157. These may be linked to food poisoning/diarrhoea.
- Yeast/ Fungal Organisms such as Candida Albicans, Geotrichum, Microsporidium and Rhodotorula. Overgrowth can cause bloating, sugar cravings, fatigue, and recurrent thrush.
What Parasites does the GI-Map test Detect?
Please see a GI-MAP stool test UK sample report here:
The GI-MAP test UK identifies a variety of parasites and Covers protozoa (Giardia, Cryptosporidium) and helminths (worms) that may cause diarrhoea, nutrient deficiencies, or IBS-like symptoms.
Pathogens and Analytes
Parasites and Worms Detected by GI-MAP:
Parasites:
- Blastocystis hominis
- Giardia lamblia
- Entamoeba histolytica
- Cryptosporidium species
- Dientamoeba fragilis
Protozoa:
- Chilomastix mesnelli
- Cyclospora species
- Endolimax nana
- Entamoeba coli
- Pentatrichomonas hominis
Bacterial Phyla:
- Bacteroidetes
- Firmicutes
- Firmicutes/Bacteroidetes Ratio
Dysbiotic/Overgrowth Bacteria:
- Bacillus species
- Enterococcus faecalis
- Enterococcus faecium
- Morganella species
- Pseudomonas species
- Pseudomonas aeruginosa
- Staphylococcus species
- Staphylococcus aureus
- Streptococcus species
- Methanobacteriaceae (family)
Worms:
- Ascaris lumbricoides (Roundworm)
- Strongyloides stercoralis (Threadworm)
- Ancylostoma duodenale and Necator americanus (Hookworm)
- Trichuris trichiura (Whipworm)
Bacterial Pathogens:
- Campylobacter
- Clostridium difficile (Toxins A & B)
- Enterohemorrhagic E. coli
- E. coli O157
- Enteroinvasive E. coli / Shigella
- Enterotoxigenic E. coli (LT/ST)
- Shiga-like Toxin E. coli (stx1, stx2)
- Salmonella
- Vibrio cholerae
- Yersinia enterocolitica
- Helicobacter pylori
- Virulence factors: babA, cagA, dupA, iceA, oipA, vacA, virB, virD
Viral Pathogens:
- Adenovirus 40/41
- Norovirus GI
- Norovirus GII
Potential Autoimmune Triggers:
- Citrobacter species
- Citrobacter freundii
- Fusobacterium species
- Klebsiella species
- Klebsiella pneumoniae
- Mycobacterium avium subsp. paratuberculosis
- Prevotella species
- Proteus species
- Proteus mirabilis
Fungi / Yeast:
- Candida albicans
- Candida species
- Geotrichum species
- Microsporidia species
- Rhodotorula species
Opportunistic Viruses:
- Cytomegalovirus (CMV)
- Epstein-Barr Virus (EBV)
Intestinal Health Markers:
Digestion:
- Elastase-1
- Steatocrit
Immune Response:
- Secretory IgA (SIgA)-gut immune defence
- Anti-gliadin SIgA- can be linked to gluten sensitivity
Inflammation:
- Calprotectin – intestinal inflammation, also used in NHS IBD pathways NICE DG11
Gastrointestinal Markers:
- ß-Glucuronidase
- Occult Blood (FIT)
Optional Antibiotic Resistance Genes (Phenotypes for Helicobacter):
- Amoxicillin
- Clarithromycin
- Fluoroquinolones
- Tetracycline
Methodology
- Quantitative Polymerase Chain Reaction (qPCR): This method amplifies and quantifies microbial DNA to identify a wide range of pathogens and markers in the gut.
How accurate is the GI-Map test?
The GI-MAP uses quantitative polymerase chain reaction (qPCR), a highly sensitive and specific method for detecting microbial DNA. This molecular technology amplifies even small amounts of DNA, making it more accurate than traditional culture-based tests, which often miss certain microbes, especially those that can’t grow outside the body.
- Sensitivity: qPCR can detect microorganisms at very low levels, meaning it can identify even small or hidden infections.
- Specificity: The test is highly specific because it targets the genetic material of microbes, reducing the chances of false positives.
The GI-MAP test is capable of detecting strict anaerobes, viruses, and virulence factors—microbes and pathogens that often go undetected in traditional stool tests. This expands its ability to give a complete picture of gut health.
The test’s sensitivity can sometimes detect microbes at low levels that may not necessarily be causing illness or symptoms, which requires careful interpretation by a healthcare professional.
Sample Collection and Shipping Guidelines
To ensure accurate results, the GI MAP stool test must be completed within a single day, and the sample should be returned to the laboratory within 24 hours due to its brief stability period.
Collection Schedule:
- Please plan to collect your sample on a Sunday or Monday or Tuesday.
Collection Timing:
- You are free to collect your sample at any point during your designated collection day.
International Shipping:
- If you are sending samples from outside the UK, you will need to organize your own courier service for the return shipment. DHL is recommended for reliable service.
Upon completion of your collection, you will receive the necessary return address and a customs letter to facilitate the shipping process.
What happens when my results are back?
We will email these to you within 3 weeks.
What are the Collection Instructions for the GI-MAP Stool Test?
If you are taking antifungal or antibiotic medication, please finish the course of medication and wait for 3 days
before starting the collection. Please refrain from taking digestive enzymes, laxatives, antacids, and aspirin for 48-hours prior to and during the specimen collection, unless otherwise instructed by your practitioner.
Never discontinue prescription medications without first consulting your doctor.
Can I book a consultation after receiving my GI MAP Test Results?
Yes, we do offer consultations in Harley street or via zoom.
- Review of Results:
Your functional medecine practioner will carefully review your results to identify any imbalances or pathogens that may be affecting your gut health. - Understanding the Findings:
The results will include information about various gut bacteria, viruses, parasites, and other markers that reflect your digestive health. We will explain what each finding means in relation to your symptoms and overall health. - Personalized Treatment Plan:
Based on your results, we will recommend a personalized treatment plan. This could include dietary changes, supplements, or other interventions designed to restore balance to your gut microbiome. - Follow-Up:
You may have a follow-up appointment to discuss your results in more detail, monitor your progress, and make any necessary adjustments to your treatment plan. - Additional Testing:
In some cases, we might suggest further testing if specific issues are identified that require more investigation. - Lifestyle Recommendations:
Alongside treatment options, we may offer lifestyle recommendations aimed at promoting a healthier gut, such as stress management techniques, and exercise.
Frequently Asked Questions About the GI-MAP Test
1. What is the GI-MAP test?
The GI-MAP is a DNA-based stool test (qPCR technology) that analyses your gut microbiome, digestion, and immune markers. It can identify bacteria, parasites, viruses, and fungi, giving a much deeper picture of gut health than standard stool cultures.
2.GI-MAP Test vs NHS Stool Test – What’s the Difference?
NHS stool tests are mainly designed to detect acute infections like Salmonella or E. coli. They don’t usually assess gut flora balance, yeast, or digestive function. GI-MAP, on the other hand, screens for a wide range of microbes and functional markers, helping to uncover the root causes of chronic gut symptoms.
3. What does the GI-MAP test measure?
The test looks at bacteria (both normal flora and opportunistic species), parasites, viruses, fungi/yeast, markers of digestion (like elastase-1), fat absorption (steatocrit), and inflammation/immune activity (calprotectin, secretory IgA). It also checks for Zonulin/leaky gut and antibiotic resistance genes.
4. Can I get the GI-MAP test on the NHS?
No, the GI-MAP test is not available on the NHS. It is only offered privately through registered practitioners and clinics.
5. How much does the GI-MAP test cost in the UK?
The test costs £345 and includes the kit, courier service, full lab report.
6. How do I collect a GI-MAP stool sample at home?
Only a small stool sample is needed. The sample is mixed with a stabilising solution, so it can be shipped safely at room temperature by courier.
7. How long does it take to get results?
Once the lab receives your sample, results are usually ready within 2–3 weeks.
8. Do I need to stop supplements or medications before the test?
Yes, certain supplements and medications can affect results. For example, antibiotics, antifungals, and probiotics may need to be paused before testing.
9. Is the GI-MAP test suitable for children?
Yes, the test can be used in children. However, treatment options may be different for children than for adults, so results should always be interpreted with a qualified practitioner.
10. Will the GI-MAP test help with IBS or other gut symptoms?
Yes. Many people with IBS, bloating, reflux, diarrhoea, or constipation have normal NHS stool results. GI-MAP often reveals imbalances (such as elevated zonulin, yeast, parasites, or low digestive enzymes) that can guide a more targeted and personalised approach.
How long do GI-MAP test results take?
The turnaround time for results from the GI-MAP test is 2- 3weeks. The results will be e-mailed to you.
Who should use the GI-Map test?
If you have symptoms of IBS and would like to test for leaky gut and inflammation as well as parasites, yeast and bacteria this test is a good choice. If your GP has already ruled out IBD, a gut pathohens test may be another affordable option.
How can I order GI-MAP test?
Our GI-MAP testing can be sent to you at home – we ship all over the UK and Europe. If you would like to order a test please order online call us on 0345 1297996 or Contact us
How does the test work?
Patients need to send in only one sample to the laboratory.
Have any questions? Call us now!
0345 1297996
FAQ
How is the GI-MAP test performed?
Patients need to send in one stool sample to the laboratory.
If you have any further questions or concerns, please feel free to contact our office.
Is Helicobacter covered on the GI-Map stool test?
Yes, Helicobacter is also covered on the stool test.
Can I get this test on the NHS?
Unfortunately, these tests are not currently offered on the NHS.
How are the stool samples preserved?
We will post you special containers that contain preservative liquid. You will need to put your stool specimens into these containers and courier them back to our lab for examination.
What happens if I need help with test?
We offer consultations at our sister clinic, ibs-solutions.co.uk in Harley street and online by virtual appoiintments.